Figure 1 2 Cirrhosis-related malaise, fatigue, or lethargy 2.1 Definitions and prevalence Malaise embodies a pervasive sense of discomfort, weakness, or unease, the precise origin of which proves elusive and closely intertwines with mental well-being ( 2.2 Mechanism and causes Muscle functionality and contractility can suffer impairment either at or beyond the neuromuscular junction, termed peripheral fatigue, or proximal to it, referred to as central fatigue
These may include: Nausea or upset stomach Diarrhea or constipation Heartburn or acid reflux Fatigue Most of these symptoms are temporary and tend to improve as your body adjusts to the medication
Many people do better with gentle carbohydrates when nausea or fullness is more intense
Patients taking Wegovy should inform their endoscopy team well in advance of their scheduled procedure to allow appropriate assessment and individualised advice
Although uncommon, its important to be aware of symptoms that warrant medical attention: Any concerning or prolonged symptoms should be discussed with a medical provider
On day 14, after the first or second dose, the neutralizing antibody titers in rhesus monkey serum were 1:5 to 1:40 (single dose) and 1:10 to 1:160 (two doses)